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aristoteleo / PantheonOS

A general, evolvable, and distributed agent framework & harness for data science.

Why this job: says: agent framework; topics: ai-agents, agent

What it does

  • Evolvable. Pantheon-Evolve module enables agents to improve algorithms and code through genetic-algorithm-driven agentic code evolution
  • Multi-Agent Teams. PantheonTeam, Sequential, Swarm, Mixture-of-Agents (MoA), and AgentAsTool team patterns for flexible orchestration
  • Distributed Architecture. NATS-based messaging for scalable, fault-tolerant deployments across machines. With Pantheon-Fleet, agents can directly control a distributed network of machines.
  • Friendly Interfaces. Interactive CLI (pantheon cli) and Chatroom UI (pantheon ui)
  • Pantheon Store. A community marketplace with 1,000+ curated agents, teams, and skills for biomedical AI, installable via UI or CLI

Get started

No single install command. Read the steps in the README (opens in new tab)

Maintenance
Active
Last commit 34 days ago
Stars
493
+1 this week
Licence
BSD-2-Clause
Allows business use
Downloads for
3 systems
Mac, Windows, Linux
Latest tag
fleet-v0.4.0-native.1
Released 53 days ago
Built with
Python
96% of the code

Is it looked after?

Contributors
2
Last 90 days
Issues
52% closed
19 still open
Pull requests
133 merged
8 waiting
Releases
185
30+ in the last year

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More: download files, languages, topics and project record

Download files, fleet-v0.4.0-native.1

  • Mac2 files, 9 downloads
  • Windows2 files, 7 downloads
  • Linux2 files, 12 downloads

All files on GitHub (opens in new tab)

Languages

  • Python 96%
  • Go 2%
  • Shell 1%
  • Dockerfile <1%

Topics

  • pantheonos
  • agent
  • singlecell
  • spatial-transcriptomics
  • ai
  • ai-agents
  • bioinformatics
  • biology
  • data-science
  • llm
  • harness
  • harness-engineering

Project record

  • JobAgent frameworks
  • StatusListed
  • Commits1,448
  • Forks67
  • Watching2
  • Stars in 28 days+6
  • CreatedJul 30, 2025
  • First seen by usNov 7, 2026
  • CheckedNov 9, 2026

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