aristoteleo / PantheonOS
A general, evolvable, and distributed agent framework & harness for data science.
Why this job: says: agent framework; topics: ai-agents, agent



What it does
- Evolvable. Pantheon-Evolve module enables agents to improve algorithms and code through genetic-algorithm-driven agentic code evolution
- Multi-Agent Teams. PantheonTeam, Sequential, Swarm, Mixture-of-Agents (MoA), and AgentAsTool team patterns for flexible orchestration
- Distributed Architecture. NATS-based messaging for scalable, fault-tolerant deployments across machines. With Pantheon-Fleet, agents can directly control a distributed network of machines.
- Friendly Interfaces. Interactive CLI (pantheon cli) and Chatroom UI (pantheon ui)
- Pantheon Store. A community marketplace with 1,000+ curated agents, teams, and skills for biomedical AI, installable via UI or CLI
Get started
No single install command. Read the steps in the README (opens in new tab)
- Maintenance
- Active
- Last commit 34 days ago
- Stars
- 493
- +1 this week
- Licence
- BSD-2-Clause
- Allows business use
- Downloads for
- 3 systems
- Mac, Windows, Linux
- Latest tag
- fleet-v0.4.0-native.1
- Released 53 days ago
- Built with
- Python
- 96% of the code
Is it looked after?
- Contributors
- 2
- Last 90 days
- Issues
- 52% closed
- 19 still open
- Pull requests
- 133 merged
- 8 waiting
- Releases
- 185
- 30+ in the last year
- Contributing guide (opens in new tab)
- No security policy
- Code of conduct (opens in new tab)
Similar repos
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| ElliotXie / CASSIA | 109 | 6 days ago | MIT | No downloads |
More: download files, languages, topics and project record
Download files, fleet-v0.4.0-native.1
- Mac2 files, 9 downloads
- Windows2 files, 7 downloads
- Linux2 files, 12 downloads
Languages
- Python 96%
- Go 2%
- Shell 1%
- Dockerfile <1%
Topics
- pantheonos
- agent
- singlecell
- spatial-transcriptomics
- ai
- ai-agents
- bioinformatics
- biology
- data-science
- llm
- harness
- harness-engineering
Project record
- JobAgent frameworks
- StatusListed
- Commits1,448
- Forks67
- Watching2
- Stars in 28 days+6
- CreatedJul 30, 2025
- First seen by usNov 7, 2026
- CheckedNov 9, 2026
