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tbepler / topaz

Pipeline for particle picking in cryo-electron microscopy images using convolutional neural networks trained from positive and unlabeled examples. Also featuring micrograph and tomogram denoising with DNNs.

Why this job: works in the areas we cover, but does not say which job it does

What it does

A pipeline for particle detection in cryo-electron microscopy images using convolutional neural networks trained from positive and unlabeled examples. Topaz also includes methods for micrograph and tomogram denoising using deep denoising models.

Get started

No single install command. Read the steps in the README (opens in new tab)

Maintenance
Active
Last commit 56 days ago
Stars
223
On GitHub
Licence
GPL-3.0
Share-alike terms
Downloads for
None listed
No release files
Latest version
v0.3.20
Released 6 months ago
Built with
Jupyter Notebook
96% of the code

Is it looked after?

Contributors
Not stated
Last 90 days
Issues
84% closed
24 still open
Pull requests
28 merged
3 waiting
Releases
11
4 in the last year
  • No contributing guide
  • No security policy
  • No code of conduct
More: languages, topics and project record

Languages

  • Jupyter Notebook 96%
  • HTML 2%
  • Python 2%
  • Singularity <1%

Topics

  • cryoem
  • particle-picking
  • machine-learning
  • cnn
  • positive-unlabeled
  • object-detection
  • pytorch
  • topaz
  • topaz-denoise
  • denoising
  • cryo-em
  • topaz-em

Project record

  • JobOther AI tools
  • StatusListed
  • Commits562
  • Forks75
  • Watching9
  • Stars in 28 days+2
  • CreatedNov 6, 2017
  • First seen by usNov 7, 2026
  • CheckedNov 8, 2026

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